Title: Kantou Kanrei
Also known as: Fujiwara-no-Norimasa (藤原憲政)

Son of Uesugi Norifusa, he was only three when his father died. His adopted brother, Uesugi Norihiro, succeeded his father as head of the clan. When his brother was banished in 1531, Norimasa inherited the title of Kantou Kanrei.

From 1541 to 1552, he battled both the Houjou and Takeda Clans. He suffered several defeats, and fled to Nagao Kagetora (Uesugi Kenshin) in 1552, leaving his son and heir behind (who was later captured and executed.)

In 1557, he adopted Nagao Kagetora and in 1561 passed the title of Kantou Kanrei to him as well as the Uesugi family name and inheritance.

He later supported Uesugi Kagetora in the Otate no Ran. But as the Kagetora faction was hard-pressed due to Takeda Katsuyori's defection, he took Kagetora's son and heir with him to negotiate with the Kagekatsu faction. However, both were killed by an assassin at Kagekatsu's camp.

His sons were killed as well in the Otate no Ran, so ironically, it would be Uesugi Kenshin's son, Uesugi Kagekatsu, who would sever the bloodline of the Uesugi house.